The Last of Us follows a group of survivors after a pandemic wipes out most of humanity, but it’s not a virus that causes the catastrophe — it’s a fungus.
The culprit is cordyceps, a real fungus that has evolved in the show to infect humans, who become zombie-like after exposure. While minor characters come and go, the series focuses mainly on Joel (Pedro Pascal), a middle-aged survivor who is charged with protecting Ellie (Bella Ramsey), a teen girl who is seemingly immune to cordyceps.
The sci-fi drama is based on the 2013 video game of the same name, which was written by Neil Druckmann. The Naughty Dog copresident is also a creator and executive producer of the HBO series, helping to ensure the show maintains the spirit of the game while also deviating where necessary.
Keep scrolling to see how The Last of Us cast compares to their video game counterparts:
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